June 16, 2018 – Endoscopic Surveillance Detects Early Gastric Cancer

A study found that endoscopic surveillance can detect gastric cancer at an early curable stage. 279 patients (previous diagnosed with either atrophic gastritis, intestinal metaplasia, or dysplasia) underwent at least one surveillance endoscopy. 84% of the patients were Caucasian. The first surveillance endoscopy was conducted after a mean interval of 35 months with a mean of 2.9 endoscopies per patient. 26% of patients were found to be infected with Helicobacter pylori. Surveillance also helped the diagnosis of 4% of patients with atrophic gastritis, 87% with intestinal metaplasia, and 9% with dysplasia. Four participants were detected to have high-grade adenoma/dysplasia or invasive neoplasia over a mean follow-up of 57 months. Two of these patients were treated successfully with endoscopic submucosal dissection; the other two patients went through total gastrectomy. However, it is reported that examination of tissues is not enough to discriminate between low-risk and high-risk cancer patients. Serological tests are noninvasive and could help identify risk levels while reducing the dependence on endoscopic resources. Gastric and oral gastric microbes can help diagnose stomach cancer and its precursors less invasively as well.
Symptoms, Screening & Early Detection
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